ScopiaRx simplifies a complex problem. For a patient on 10 medications, there are hundreds of interactions and side effects to consider. Currently, most of this risk information is ignored, but with ScopiaRx, health care providers can efficiently address safety issues.
The drug information in the ScopiaRx database comes from FDA approved drug labels and summaries of aftermarket case reports that are derived from the FDA's FAERS system. For herbals and supplements, safety information is obtained from the National Institutes of Health Office of Dietary Supplements and the National Institutes of Health Center for Complementary and Integrative Health.
The ScopiaRx algorithm sorts through this data to find the information relevant to a particular patient, organizes the information by the drug related adverse events (DRAEs), scores the likelihood of each DRAE risk, and then sorts the DRAEs by risk level. The composite risk for a DRAE contains multiple safety factors including high frequencies of the DRAE due to individual drugs, high aftermarket reporting frequencies for individual drugs, drug-drug interactions that increase the likelihood of a DRAE, drug-clinical interactions, drug-herbal interactions, drug-lifestyle interactions, drug-demographic interactions, and pharmacogenetic factors that increase or decrease metabolism. A unique feature of the ScopiaRx database is a comprehensive set of drug-clinical interactions that derive from the box warnings, contraindications, warnings and precautions sections of FDA approved product inserts. These drug-clinical interactions are linked to ICD10 codes.